29 April 2025 · Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.

3 January 2025 · Most drug interactions with local anaesthetics (LA) cartridges are not clinically relevant in general dentistry. We advise on management options where needed.

15 November 2023 · Duloxetine, mirtazapine, trazodone or venlafaxine can be used with caution but other options are preferred. Recommendations apply to full term, healthy infants.

31 October 2023 · When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

21 March 2023 · Oxybutynin is preferred for urinary disorders during breastfeeding. Recommendations apply to full term and healthy infants only.

17 February 2023 · Suggested methods for switching safely between SNRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.