Intrathecal medicine considerations
Choosing an injectable medicine for intrathecal administration
11 August 2022The intrathecal route is a high risk route of administration. It is essential to consider the properties of the medicinal product when assessing the risk
Understanding risks with intrathecal administration
13 June 2025The intrathecal route is a high-risk route of administration. Incorrect administration of medicines unsafe for this route can result in patient death.
Managing an intrathecal chemotherapy service
13 June 2025The intrathecal route is a high-risk route of administration. There are minimum requirements for providing intrathecal chemotherapy.
Shelf lives of aseptically prepared medicines in NRFit syringes
19 December 2024Provision of intrathecal and epidural injections in NRFit syringes may involve extrapolation of stability data from luer lock systems
Medicine-specific information
Each article lists available products to help inform an intrathecal administration risk assessment
Anaesthesia and Pain
- Ziconotide: informing intrathecal risk assessment
- Clonidine: informing intrathecal risk assessment
- Morphine: informing intrathecal risk assessment
- Phenol: informing intrathecal risk assessment
- Ropivacaine: informing intrathecal risk assessment
- Lidocaine: informing intrathecal risk assessment
- Diamorphine hydrochloride: informing intrathecal risk assessment
- Hydromorphone: informing intrathecal risk assessment
- Bupivacaine: informing intrathecal risk assessment
- Levobupivacaine: informing intrathecal risk assessment
Cancers
- Managing an intrathecal chemotherapy service
- Understanding risks with intrathecal administration
- Hydrocortisone: informing intrathecal risk assessment
- Methotrexate: informing intrathecal risk assessment
- Etoposide: informing intrathecal risk assessment
- Rituximab: informing intrathecal risk assessment
- Topotecan: informing intrathecal risk assessment
- Hydrocortisone acetate: informing intrathecal risk assessment
- Cytarabine: informing intrathecal risk assessment
- Trastuzumab: informing intrathecal risk assessment
Infection and infectious diseases
- Gentamicin: informing intrathecal risk assessment
- Colistimethate sodium: informing intrathecal risk assessment
- Fluorescein: informing intrathecal risk assessment
- Vancomycin: informing intrathecal risk assessment
- Amikacin: informing intrathecal risk assessment